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Community responsibility for a safety culture in academic chemistry.

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This is another approximate transcript of a part of the conversation I had with Chemjobber that became a podcast. This segment (from about 29:55 to 52:00) includes our discussion of what a just punishment might look like for PI Patrick Harran for his part in the Sheri Sangji case. From there, our discussion shifted to the question of how to make the culture of academic chemistry safer:

Chemjobber: One of the things that I guess I’ll ask is whether you think we’ll get justice out of this legal process in the Sheri Sangji case.

Janet: I think about this, I grapple with this, and about half the time when I do, I end up thinking that punishment — and figuring out the appropriate punishment for Patrick Harran — doesn’t even make my top-five list of things that should come out of all this. I kind of feel like a decent person should feel really, really bad about what happened, and should devote his life forward from here to making the conditions that enabled the accident that killed Sheri Sangji go away. But, you know, maybe he’s not a decent person. Who the heck can tell? And certainly, once you put things in the context where you have a legal team defending you against criminal charges — that tends to obscure the question of whether you’re a decent person or not, because suddenly you’ve got lawyers acting on your behalf in all sorts of ways that don’t look decent at all.

Chemjobber: Right.

Janet: I think the bigger question in my mind is how does the community respond? How does the chemistry department at UCLA, how does the larger community of academic chemistry, how do Patrick Harran’s colleagues at UCLA and elsewhere respond to all of this? I know that there are some people who say, “Look, he really fell down on the job safety-wise, and in terms of creating an environment for people working on his behalf, and someone died, and he should do jail time.” I don’t actually know if putting him in jail changes the conditions on the outside, and I’ve said that I think, in some ways, tucking him away in jail for however many months makes it easier for the people who are still running academic labs while he’s incarcerated to say, “OK, the problem is taken care of. The bad actor is out of the pool. Not a problem,” rather than looking at what it is about the culture of academic chemistry that has us devoting so little of our time and energy to making sure we’re doing this safely. So, if it were up to me, if I were the Queen of Just Punishment in the world of academic chemistry, I’ve said his job from here on out should be to be Safety in the Research Culture Guy. That’s what he gets to work on. He doesn’t get to go forward and conduct new research on some chemical question like none of this ever happened. Because something happened. Something bad happened, and the reason something bad happened, I think, is because of a culture in academic chemistry where it was acceptable for a PI not to pay attention to safety considerations until something bad happened. And that’s got to change.

Chemjobber: I think it will change. I should point out here that if your proposed punishment were enacted, it would be quite a punishment, because he wouldn’t get to choose what he worked on anymore, and that, to a great extent, is the joy of academic research, that it’s self-directed and that there is lots and lots of freedom. I don’t get to choose the research problems I work on, because I do it for money. My choices are more or less made by somebody else.

Janet: But they pay you.

Chemjobber: But they pay me.

Janet: I think I’d even be OK saying maybe Harran gets to do 50% of his research on self-directed research topics. But the other 50% is he has to go be an evangelist for changing how we approach the question of safety in academic research.

Chemjobber: Right.

Janet: He’s still part of the community, he’s still “one of us,” but he has to show us how we are treading dangerously close to the conditions that led to the really bad thing that happened in his lab, so we can change that.

Chemjobber: Hmm.

Janet: And not just make it an individual thing. I think all of the attempts to boil what happened down to all being the individual responsibility of the technician, or of the PI, or it’s a split between the individual responsibility of one and the individual responsibility of the other, totally misses the institutional responsibility, and the responsibility of the professional community, and how systemic factors that the community is responsible for failed here.

Chemjobber: Hmm.

Janet: And I think sometimes we need individuals to step up and say, part of me acknowledging my personal responsibility here is to point to the ways that the decisions I made within the landscape we’ve got — of what we take seriously, of what’s rewarded and what’s punished — led to this really bad outcome. I think that’s part of the power here is when academic chemists say, “I would be horrified if you jailed this guy because this could have happened in any of our labs,” I think they’re right. I think they’re right, and I think we have to ask how it is that conditions in these academic communities got to the point where we’re lucky that more people haven’t been seriously injured or killed by some of the bad things that could happen — that we don’t even know that we’re walking into because safety gets that short shrift.

Chemjobber: Wow, that’s heavy. I’m not sure whether there are industrial chemists whose primary job is to think about safety. Is part of the issue we have here that safety has been professionalized? We have industrial chemical hygienists and safety engineers. Every university has an EH&S [environmental health and safety] department. Does that make safety somebody else’s problem? And maybe if Patrick Harran were to become a safety evangelist, it would be a way of saying it’s our problem, and we all have to learn, we have to figure out a way to deal with this?

Janet:Yeah. I actually know that there exist safety officers in academic science departments, partly because I serve on some university committees with people who fill that role — so I know they exist. I don’t know how much the people doing research in those departments actually talk with those safety officers before something goes wrong, or how much of it goes beyond “Oh, there’s paperwork we need to make sure is filed in the right place in case there’s an inspection,” or something like that. But it strikes me that safety should be more collaborative. In some ways, wouldn’t that be a more gripping weekly seminar to have in a chemistry department for grad students working in the lab, even just once a month on the weekly seminar, to have a safety roundtable? “Here are the risks that we found out about in this kind of work,” or talking about unforeseen things that might happen, or how do you get started finding out about proper precautions as you’re beginning a new line of research? What’s your strategy for figuring that out? Who do you talk to? I honestly feel like this is a part of chemical education at the graduate level that is extremely underdeveloped. I know there’s been some talk about changing the undergraduate chemistry degree so that it includes something like a certificate program in chemical safety, and maybe that will fix it all. But I think the only thing that fixes it all is really making it part of the day to day lived culture of how we build new knowledge in chemistry, that the safety around how that knowledge gets built is an ongoing part of the conversation.

Chemjobber: Hmm.

Janet: It’s not something we talk about once and then never again. Because that’s not how research works. We don’t say, “Here’s our protocol. We never have to revisit it. We’ll just keep running it until we have enough data, and then we’re done.”

Chemjobber: Right.

Janet: Show me an experiment that’s like that. I’ve never touched an experiment like that in my life.

Chemjobber: So, how many times do you remember your Ph.D. advisor talking to you about safety?

Janet: Zero. He was a really good advisor, he was a very good mentor, but essentially, how it worked in our lab was that the grad students who were further on would talk to the grad students who were newer about “Here’s what you need to be careful about with this reaction, “ or “If you’ve got overflow of your chemical waste, here’s who to call to do the clean-up,” or “Here’s the paperwork you fill out to have the chemical waste hauled away properly.” So, the culture was the people who were in the lab day to day were the keepers of the safety information, and luckily I joined a lab where those grad students were very forthcoming. They wanted to share that information. You didn’t have to ask because they offered it first. I don’t think it happens that way in every lab, though.

Chemjobber: I think you’re right. The thorniness of the problem of turning chemical safety into a day to day thing, within the lab — within a specific group — is you’re relying on this group of people that are transient, and they’re human, so some people really care about it and some people tend not to care about it. I had an advisor who didn’t talk about safety all the time but did, on a number of occasions, yank us all short and say, “Hey, look, what you’re doing is dangerous!” I clearly remember specific admonishments: “Hey, that’s dangerous! Don’t do that!”

Janet: I suspect that may be more common in organic chemistry than in physical chemistry, which is my area. You guys work with stuff that seems to have a lot more potential to do interesting things in interesting ways. The other thing, too, is that in my research group we were united by a common set of theoretical approaches, but we all worked in different kinds of experimental systems which had different kinds of hazards. The folks doing combustion reactions had different things to worry about than me, working with my aqueous reaction in a flow-through reactor, while someone in the next room was working with enzymatic reactions. We were all over the map. Nothing that any of us worked with seemed to have real deadly potential, at least as we were running it, but who knows?

Chemjobber: Right.

Janet: And given that different labs have very different dynamics, that could make it hard to actually implement a desire to have safety become a part of the day to day discussions people are having as they’re building the knowledge. But this might really be a good place for departments and graduate training programs to step up. To say, “OK, you’ve got your PI who’s running his or her own fiefdom in the lab, but we’re the other professional parental unit looking out for your well being, so we’re going to have these ongoing discussions with graduate cohorts made up of students who are working in different labs about safety and how to think about safety where the rubber hits the road.” Actually bringing those discussions out of the research group, the research group meeting, might provide a space where people can become reflective about how things go in their own labs and can see something about how things are being done differently in other labs, and start piecing together strategies, start thinking about what they want the practices to be like when they’re the grown-up chemists running their own labs. How do they want to make safety something that’s part of the job, not an add on that’s being slapped on or something that’s being forgotten altogether.

Chemjobber: Right.

Janet: But of course, graduate training programs would have to care enough about that to figure out how to put the resources on it, to make it happen.

Chemjobber: I’m in profound sympathy with the people who would have to figure out how to do that. I don’t really know anything about the structure of a graduate training program other than, you know, “Do good work, and try to graduate sooner rather than later.” But I assume that in the last 20 to 30 years, there have been new mandates like “OK, you all need to have some kind of ethics component” —

Janet: — because ethics coursework will keep people from cheating! Except that’s an oversimplified equation. But ethics is a requirement they’re heaping on, and safety could certainly be another. The question is how to do that sensibly rather than making it clear that we’re doing this only because there’s a mandate from someone else that we do it.

Chemjobber: One of the things that I’ve always thought about in terms of how to better inculcate safety in academic labs is maybe to have training that happens every year, that takes a week. New first-years come in and you get run through some sort of a lab safety thing where you go and you set up the experiment and weird things are going to happen. It’s kind of an artificial environment where you have to go in and run a dangerous reaction as a drill that reminds you that there are real-world consequences. I think Chembark talked about how, in Caltech Safety Day, they brought out one of the lasers and put a hole through an apple. Since Paul is an organic chemist, I don’t think he does that very often, but his response was “Oh, if I enter one of these laser labs, I should probably have my safety glasses on.” There’s a limit to the effectiveness of that sort of stuff. you have to really, really think about how to design it, and a week out of a year is a long time, and who’s going to run it? I think your idea of the older students in the lab being the ones who really do a lot of the day to day safety stuff is important. What happens when there are no older students in the lab?

Janet: That’s right, when you’re the first cohort in the PI’s lab.

Chemjobber: Or, when there hasn’t been much funding for students and suddenly now you have funding for students.

Janet: And there’s also the question of going from a sparsely populated lab to a really crowded lab when you have the funding but you don’t suddenly have more lab space. And crowded labs have different kinds of safety concerns than sparsely populated labs.

Chemjobber: That’s very true.

Janet: I also wonder whether the “grown-up” chemists, the postdocs and the PIs, ought to be involved in some sort of regular safety … I guess casting it as “training” is likely to get people’s hackles up, and they’re likely to say, “I have even less time for this than my students do.”

Chemjobber: Right.

Janet: But at the same time, pretending that they learned everything they need to know about safety in grad school? Really? Really you did? When we’re talking now about how maybe the safety training for graduate students is inadequate, you magically got the training that tells you everything you need to know from here on out about safety? That seems weird. And also, presumably, the risks of certain kinds of procedures and certain kinds of reagents — that’s something about which our knowledge continues to increase as well. So, finding ways to keep up on that, to come up with safer techniques and better responses when things do go wrong — some kind of continuing education, continuing involvement with that. If there was a way to do it to include the PIs and the people they’re employing or training, to engage them together, maybe that would be effective.

Chemjobber: Hmm.

Janet: It would at least make it seem less like, “This is education we have to give our students, this is one more requirement to throw on the pile, but we wouldn’t do it if we had the choice, because it gets in the way of making knowledge.” Making knowledge is good. I think making knowledge is important, but we’re human beings making knowledge and we’d like to live long enough to appreciate that knowledge. Graduate students shouldn’t be consumable resources in the knowledge-building the same way that chemical reagents are.

Chemjobber: Yeah.

Janet: Because I bet you the disposal paperwork on graduate students is a fair bit more rigorous than for chemical waste.

Why does lab safety look different to chemists in academia and chemists in industry?

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Here’s another approximate transcript of the conversation I had with Chemjobber that became a podcast. In this segment (from about 19:30 to 29:30), we consider how reaction to the Sheri Sangji case sound different when they’re coming from academic chemists than when they’re coming from industry, and we spin some hypotheses about what might be going on behind those differences:

Chemjobber: I know that you wanted to talk about the response of industrial chemists versus academic chemists to the Sheri Sangji case.

Janet: This is one of the things that jumps out at me in the comment threads on your blog posts about the Sangji case. (Your commenters, by the way, are awesome. What a great community of commenters engaging with this stuff.) It really does seem that the commenters who are coming from industry are saying, “These conditions that we’re hearing about in the Harran lab (and maybe in academic labs in general) are not good conditions for producing knowledge as safely as we can.” And the academic commenters are saying, “Oh come on, it’s like this everywhere! Why are you going to hold this one guy responsible for something that could have happened to any of us?” It shines a light on something interesting about how academic labs building knowledge function really differently from industrial labs building knowledge.

Chemjobber: Yeah, I don’t know. It’s very difficult for me to separate out whether it’s culture or law or something else. Certainly I think there’s a culture aspect of it, which is that every large company and most small companies really try hard to have some sort of a safety culture. Whether or not they actually stick to it is a different story, but what I’ve seen is that the bigger the company, the more it really matters. Part of it, I think, is that people are older and a little bit wiser, they’re better at looking over each other’s shoulders and saying, “What are you doing over there?” and “So, you’re planning to do that? That doesn’t sound like a great idea.” It seems like there’s less of that in academia. And then there’s the regulatory aspect of it. Industrial chemists are workers, the companies they’re working for are employers, and there’s a clear legal aspect to that. Even as under-resourced as OSHA is, there is an actual legal structure prepared to deal with accidents. If the Sangji incident had happened at a very large company, most people think that heads would have rolled, letters would have been placed in evaluation files, and careers would be over.

Janet: Or at least the lab would probably have been shut down until a whole bunch of stuff was changed.

Chemjobber: But in academia, it looks like things are different.

Janet: I have some hunches that perhaps support some of your hunches here about where the differences are coming from. First of all, the set-up in academia assumes radical autonomy on the part of the PI about how to run his or her lab. Much of that is for the good as far as allowing different ways to tackle the creative problems about how to ask the scientific questions to better shake loose the piece of knowledge you’re trying to shake loose, or allowing a range of different work habits that might be successful for these people you’re training to be grown-up scientists in your scientific field. And along with that radical autonomy — your lab is your fiefdom — in a given academic chemistry department you’re also likely to have a wide array of chemical sub-fields that people are exploring. So, depending on the size of your department, you can’t necessarily count on there being more than a couple other PIs in the department who really understand your work well enough that they would have deep insight into whether what you’re doing is safe or really dangerous. It’s a different kind of resource that you have available right at hand — there’s maybe a different kind of peer pressure that you have in your immediate professional and work environment acting on the industrial chemist than on the academic chemist. I think that probably plays some role in how PIs in academia are maybe aren’t as up on potential safety risks of new work they’re doing as they might be otherwise. And then, of course, there’s the really different kinds of rewards people are working for in industry versus academia, and how the whole tenure race ends up asking more and more of people with the same 24 hours in the day as anyone else. So, people on the tenure track start asking, “What are the things I’m really rewarded for? Because obviously, if I’m going to succeed, that’s where I have to focus my attention.”

Chemjobber: It’s funny how the “T” word keeps coming up.

Janet: By the same token, in a university system that has consistently tried to male it easier to fire faculty at whim because they’re expensive, I sort of see the value of tenure. I’m not at all argue that tenure is something that academic chemists don’t need. But, it may be that the particulars of how we evaluate people for tenure are incentivizing behaviors that are not helping the safety of the people building the knowledge or the well-being of the people who are training to be grown-ups in these professional communities.

Chemjobber: That’s right. We should just say specifically that in this particular case, Patrick Harran already had tenure, and I believe he is still a chaired professor at UCLA.

Janet: I think maybe the thing to point out is that some of these expectations, some of these standard operating procedures within disciplines in academia, are heavily shaped by the things that are rewarded for tenure, and then for promotion to full professor, and then whatever else. So, even if you’re tenured, you’re still soaking in that same culture that is informing the people who are trying to get permission to stay there permanently rather than being thanked for their six years of service and shown the door. You’re still soaking in that culture that says, “Here’s what’s really important.” Because if something else was really important, then by golly that’s how we’d be choosing who gets to stay here for reals and who’s just passing through.

Chemjobber: Yes.

Janet: I don’t know as much about the typical life cycle of the employee in industrial chemistry, but my sense is that maybe the fact that grad students and postdocs and, to some extent, technicians are sort of transient in the community of academic chemistry might make a difference as well — that they’re seen as people who are passing through, and that the people who are more permanent fixtures in that world either forget that they come in not knowing all the stuff that the people who have been there for a long, long time know, or they’re sort of making a calculation, whether they realize it or not, about how important it is to convey some of this stuff they know to transients in their academic labs.

Chemjobber: Yeah, I think that’s true. Numerically, there’s certainly a lot less turnover in industry than there is in academic labs.

Janet: I would hope so!

Chemjobber: Especially from the bench-worker perspective. It’s unfortunate that layoffs happen (topic for another podcast!), but that seems to be the main source of turnover in industry these days.

Safety in academic chemistry labs (with some thoughts on incentives).

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Earlier this month, Chemjobber and I had a conversation that became a podcast. We covered lots of territory, from the Sheri Sangji case, to the different perspectives on lab safety in industry and academia, to broader questions about how to make attention to safety part of the culture of chemistry. Below is a transcript of a piece of that conversation (from about 07:45 to 19:25). I think there are some relevant connections here to my earlier post about strategies for delivering ethics training — a post which Jyllian Kemsley notes may have some lessons for safety-training, too.

Chemjobber: I think, academic-chemistry-wise, we might do better at looking out after premeds than we do at looking out after your typical first year graduate student in the lab.

Janet: Yeah, and I wonder why that is, actually, given the excess of premeds. Maybe that’s the wrong place to put our attention.* But maybe the assumption is that, you know, not everyone taking a chemistry lab course is necessarily going to come into the lab knowing everything they need to know to be safe. And that’s probably a safe assumption to make even about people who are good in chemistry classes. So, that’s one of those things that I think we could do a lot better at, just recognizing that there are hazards and that people who have never been in these situations before don’t necessarily know ho to handle them.

Chemjobber: Yeah, I agree. I don’t know what the best way is to make sure to inculcate that sort of lab safety stuff into graduate school. Because graduate school research is supposed to be kind of free-flowing and spontaneous — you have a project and you don’t really know where it’s going to lead you. On the other hand, a premed organic chemistry class is a really artificial environment where there is an obvious beginning and an obvious end and you stick the safety discussion right at the beginning. I remember doing this, where you pull out the MSDS that’s really scary sounding and you scare the pants off the students.

Janet: I don’t even think alarming them is necessarily the way to go, but just saying, hey, it matters how you do this, it matters where you do this, this is why it matters.

Chemjobber: Right.

Janet: And I guess in research, you’re right, there is this very open-ended, free-flowing thing. You try to build knowledge that maybe doesn’t exist yet. You don’t know where it’s going to go. You don’t necessarily know what the best way to build that knowledge is going to be. I think where we fall short sometimes is that there may be an awful lot of knowledge out there somewhere, that if you take this approach, with these techniques or with these chemicals, here are some dangers that are known. Here are some risks that someone knows about. You may not know them yet, but maybe we need to do better in the conceiving-of-the-project stage at making that part of the search of prior literature. Not just, what do we know about this reaction mechanism, but what do we know about the gnarly reagents you need to be able to work with to pursue a similar kind of reaction.

Chemjobber: Yeah. My understanding is that in the UK, before you do every experiment, there’s supposed to be a formalized written risk analysis. UK listeners can comment on whether those actually happen. But it seems like they do, because, you know, when you see online conversation of it, it’s like, “What? You guys don’t do that in the US?” No, we don’t.

Janet: There’s lots of things we don’t do. We don’t have a national health service either.

Chemjobber: But how would you make the bench-level researcher do that risk analysis? How does the PI make the bench-level researcher do that? I don’t know. … Neal Langerman is a prominent chemical safety expert. Beryl Benderly is somebody who writes on the Sheri Sangji case who’s talked about this, which is that basically that we should fully and totally incentivize this by tying academic lab safety to grants and tenure. What do you think?

Janet: I think that the intuition is right that if there’s not some real consequence for not caring about safety, it’s going to be the case that some academic researchers, making a rational calculation about what they have to do and what they’re going to be rewarded on and what they’re going to be punished for, are going to say, this would be nice in a perfect world. But there really aren’t enough hours in the day, and I’ve got to churn out the data, and I’ve got to get it analyzed and get the manuscript submitted, especially because I think that other group that was working on something like this might be getting close, and lord knows we don’t want to get scooped — you know, if there’s no consequence for not doing it, if there’s no culture of doing it, if there’s no kind of repercussion among their peers and their professional community for not doing it, a large number of people are going to make the rational calculation that there’s no point in doing it.

Chemjobber: Yeah.

Janet: Maybe they’ll do it as a student exercise or something, but you know what, students are pretty clever, and they get to a point where they actually watch what the PI who is advising them does, and form something like a model of “this is what you need to do to be a successful PI”. And all the parts of what their PI does that are invisible to them? At least to a first approximation, those are not part of the model.

Chemjobber: Right. I’ve been on record as saying that I find tying lab safety to tenure especially to be really dangerous, because you’re giving an incredible incentive to hide incidents. I mean, “For everybody’s sake, sweep this under the rug!” is what might come of this. Obviously, if somebody dies, you can’t hide that.

Janet: Hard to hide unless you’ve got off-the-books grad students, which … why would you do that?

Chemjobber: Are you kidding? There’s a huge supply of them already! But, my concern with tying lab safety to tenure is that I have a difficult time seeing how you would make that a metric other than, if you’ve reported an accident, you will not get tenure, or, if you have more than two accidents a year, you will not get tenure. For the marginal cases, the incentive becomes very high to hide these accidents.

Janet: Here’s a way it might work, though — and I know this sort of goes against the grain, since tenure committees much prefer something they can count to things they have to think about, which is why the number of publications and the impact factor becomes way more important somehow than the quality or importance of the publications as judged by experts in the field. But, something like this might work: if you said, what we’re going to look at in evaluating safety and commitment to safety for your grants and tenure is whether you’ve developed a plan. We’re going to look at what you’ve done to talk with the people in your lab about the plan, and at what you’ve done to involve them in executing the plan. So we’re going to look at it as maybe a part of your teaching, a part of your mentoring — and here, I know some people are going to laugh, because mentoring is another one of those things that presumably is supposed to be happening in academic chemistry programs, but whether it’s seriously evaluated or not, other than by counting the number of students who you graduate per year, is … you know, maybe it’s not evaluated as rigorously as it might be. But, if it became a matter of “Show us the steps you’re taking to incorporate an awareness and a seriousness about safety into how you train these graduate students to be grown-up chemists,” that’s a different kind of thing from, “Oh, and did you have any accidents or not?” Because sometimes the accidents are because you haven’t paid attention at all to safety, but sometimes the accidents are really just bad luck.

Chemjobber: Right.

Janet: And you know, maybe this isn’t going to happen every place, but at places like my university, in our tenure dossiers, they take seriously things like grant proposals we have written as part of our scholarly work, whether or not they get funded. You include them so the people evaluating your tenure dossier can evaluate the quality of your grant proposal, and you get some credit for that work even if it’s a bad pay-line year. So a safety plan and evidence of its implementation you might get credit for even if it’s been a bad year as far as accidents.

Chemjobber: I think that’s fair. You know, I think that everybody hopes that with a high-stakes thing like tenure, there’s lots of “human factor” and relatively little number-crunching.

Janet: Yeah, but you know, then you’re on the committee that has to evaluate a large number of dossiers. Human nature kicks in and counting is easier than evaluating, isn’t it?

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* Let the record reflect that despite our joking about “excesses” of premeds, neither I nor Chemjobber have it in for premeds. Especially so now that neither of us is TAing a premed course.

Facing felony charges in lab death of Sheri Sangji, UCLA settles, Harran stretches credulity.

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There have been recent developments in the criminal case against UCLA and chemistry professor Patrick Harran in connection with the fatal laboratory accident that resulted in the death of Sheri Sangji (which we’ve discussed here and here). The positive development is that UCLA has reached a plea agreement with prosecutors. (CORRECTION: UCLA has reached a settlement agreement with the prosecutors, not a plea agreement. Sorry for the confusion.) However, Patrick Harran’s legal strategy has taken a turn that strikes me as ill-advised.

From the Los Angeles Times:

Half of the felony charges stemming from a 2008 lab accident that killed UCLA research assistant Sheri Sangji were dropped Friday when the University of California regents agreed to follow comprehensive safety measures and endow a $500,000 scholarship in her name.

“The regents acknowledge and accept responsibility for the conditions under which the laboratory operated on Dec. 29, 2008,” the agreement read in part, referring to the date that Sangji, 23, suffered fatal burns.

Charges remain against her supervisor, chemistry professor Patrick Harran. His arraignment was postponed to Sept. 5 to allow the judge to consider defense motions, including one challenging the credibility of the state’s chief investigator on the case. …

UCLA and Harran have called her death a tragic accident and said she was a seasoned chemist who chose not to wear a protective lab coat. …

In court papers this week, Harran’s lawyers said prosecutors had matched the fingerprints of Brian Baudendistel, a senior special investigator who handled the case for the state Division of Occupational Safety and Health, with the prints of a teenager who pleaded no contest to murder in Northern California in 1985.

The defense contends that the investigator, whose report formed the basis for the charges, is the same Brian A. Baudendistel who took part in a plot to rob a drug dealer of $3,000 worth of methamphetamine, then shot him. Another teenager admitted to pulling the trigger but said it was Baudendistel’s shotgun.

Baudendistel told The Times this week that it is a case of mistaken identity and that he is not the individual involved in the 1985 case.

Cal/OSHA defended the integrity of the investigation in a statement issued Friday by spokesman Dean Fryer.

“The defendants’ most recent attempt to deflect attention from the charges brought against them simply does not relate in any way to the circumstances of Ms. Sangji’s death or the actual evidence collected in Cal/OSHA’s comprehensive investigation,” it read.

Deborah Blum adds:

Should  chemist-in-training approach hazardous chemicals with extreme caution? Yes. Should she expect her employer to provide her with the necessary information and equipment to engage in such caution? Most of us would argue yes. Should chemistry professors be held to the standard of employee safety as, say, chemical manufacturers or other industries? The most important “yes” to that question comes from  Cal/OSHA senior  investigator Brian Baudendistal.

Baudendistal concluded that the laboratory operation was careless enough for long enough to justify felony charges of willful negligence.  The Sangji family, angered by those suggestions that Sheri’s experience should have taught her better, pushed for prosecution. Late last year the Los Angeles District Attorney’s office  officially brought charges against Harran, UCLA, and the University of California system itself. …

[Harran’s] lawyers have responded to the Baudendistal report in part by focusing on Baudendistal himself. They claim to have found evidence that in 1985 he and two friends conspired to set up the murder of a drug dealer. All three boys were convicted and although, since they were juveniles, the records were sealed, attorneys were able to identify the killers through press coverage at the time. Although Baudendistal has insisted that Harran’s defense team tracked down the wrong man, they say they have a fingerprint match to prove it. They say further that a man who covers up his past history is not credible – and therefore neither is is report on the UCLA laboratory.

I am not a lawyer, so I’m not terribly interested in speculating on the arcane legal considerations that might be driving this move by Harran’s legal team. (Chemjobber speculates that it might be a long shot they’re playing amid plea negotiations that are not going well.)

As someone with a professional interest in crime and punishment within scientific communities, and in ethics more broadly, I do, however, think it’s worth examining the logic of Patrick Harran’s legal strategy.

The strategy, as I understand it, is to cast aspersions on the Cal/OSHA report on the basis of the legal history of the senior investigator that prepared it — specifically, his alleged involvement as a teenager in 1985 in a murder plot.

Does a past bad act like this serve as prima facie reason to doubt the accuracy of the report of the investigation of conditions in Harran’s lab? It’s not clear how it could, especially if there were other investigators on the team, not alleged to be involved in such criminal behavior, who endorsed the claims in the report.

Unless, of course, the reason Harran’s legal team thinks we should doubt the accuracy of the report is that the senior investigator who prepared it is a habitual liar. To support the claim that he cannot be trusted, they point to a single alleged lie — denying involvement in the 1985 murder plot.

But this strikes me as a particularly dangerous strategy for Patrick Harran to pursue.

Essentially, the strategy rests on the claim that if a person has lied about some particular issue, we should assume that any claim that person makes, about whatever issue, might also be a lie. I’m not unsympathetic to this claim — trust is something that is earned, not simply assumed in the absence of clear evidence of dishonesty.

However, this same reasoning cannot help Patrick Harran’s credibility, given that he is on record describing Sheri Sangji, a 23-year-old with a bachelor’s degree, as an experienced chemist. Many have noted already that claiming Sheri Sangji was a experienced chemist is ridiculous on its face.

Thus, it’s not unreasonable to conclude that Patrick Harran lied when he described Sheri Sangji as an experienced chemist. And, if this is the case, following the reasoning advocated by his legal team, we must doubt the credibility of every other claim he has made — including claims about the safety training he did or did not provide to people in his lab, conditions in his lab in 2008 when the fatal accident happened, even whether he recommended that Sangji wear a lab coat.

If Patrick Harran was not lying when he said he believed Sheri Sangji was an experienced chemist, the other possibility is that he is incredibly stupid — certainly too stupid to be in charge of a lab where people work with potentially hazardous chemicals.

Some might posit that Harran’s claims about Sangji’s chemical experience were made on the advice of his legal team. That may well be, but I’m unclear on how lying on the advice of counsel is any less a lie. (If it is, this might well mitigate the “lie of omission” of an investigator advised by his lawyers that his juvenile record is sealed.) And if one lie is all it takes to decimate credibility, Harran is surely as vulnerable as Baudendistel.

Finally, a piece of free advice to PIs worrying that they may find themselves facing criminal charges should their students, postdocs, or technicians choose not to wear lab coats or other safety gear: It is perfectly reasonable to establish, and enforce, a lab policy that states that those choosing to opt out of the required safety equipment are also opting out of access to the laboratory.

Book review: The Radioactive Boy Scout.

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When I and my three younger siblings were growing up, our parents had a habit of muttering, “A little knowledge is a dangerous thing.” The muttering that followed that aphorism usually had to do with the danger coming from the “little” amount of knowledge rather than a more comprehensive understanding of whatever field of endeavor was playing host to the hare-brained scheme of the hour. Now, as a parent myself, I suspect that another source of danger involved asymmetric distribution of the knowledge among the interested parties: while our parents may have had knowledge of the potential hazards of various activities, knowledge that we kids lacked, they didn’t always have detailed knowledge of what exactly we kids were up to. It may take a village to raise a child, but it can take less than an hour for a determined child to scorch the hell out of a card table with a chemistry kit. (For the record, the determined child in question was not me.)

The question of knowledge — and of gaps in knowledge — is a central theme in The Radioactive Boy Scout: The Frightening True Story of a Whiz Kid and His Homemade Nuclear Reactor by Ken Silverstein. Silverstein relates the story of David Hahn, a Michigan teen in the early 1990s who, largely free of adult guidance or supervision, worked tirelessly to build a breeder reactor in his back yard. At times this feels like a tale of youthful determination to reach a goal, a story of a self-motivated kid immersing himself in self-directed learning and doing an impressive job of identifying the resources he required. However, this is also a story about how, in the quest to achieve that goal, safety considerations can pretty much disappear.

David Hahn’s source of inspiration — not to mention his guide to many of the experimental techniques he used — was The Golden Book of Chemistry Experiments. Published in 1960, the text by Robert Brent conveys an almost ruthlessly optimistic view of the benefits chemistry and chemical experimentation can bring, whether to the individual or to humanity as a whole. Part of this optimism is what appears to modern eyes as an alarmingly cavalier attitude towards potential hazards and chemical safety. If anything, the illustrations by Harry Lazarus downplay the risks even more than does the text — across 112 pages, the only pictured items remotely resembling safety apparatus are lab coats and a protective mask for an astronaut.

Coupled with the typical teenager’s baseline assumption of invulnerability, you might imagine that leaving safety considerations in the subtext, or omitting them altogether, could be a problem. In the case of a teenager teaching himself chemistry from the book, relying on it almost as a bible of the concepts, history, and experimental techniques a serious chemist ought to know, the lack of focus on potential harms might well have suggested that there was no potential for harm — or at any rate that the harm would be minor compared to the benefits of mastery. David Hahn seems to have maintained this belief despite a series of mishaps that made him a regular at his local emergency room.

Ah, youth.

Here, though, The Radioactive Boy Scout reminds us that young David Hahn was not the only party operating with far too little knowledge. Silverstein’s book expands on his earlier Harper’s article on the incident with chapters that convey just how widespread our ignorance of radioactive hazards has been for most of the history of our scientific, commercial, and societal engagement with radioactivity. At nearly every turn in this history, potential benefits have been extolled (with radium elixirs sold in the early 1900s to lower blood pressure, ease arthritis pain, and produce “sexual rejuvenescence”) and risks denied, sometimes until the body count was so large and the legal damages were so high that they could no longer be denied.

Surely part of the problem here is that the hazards of radioactivity are less immediately obvious than those of corrosive chemicals or explosive chemicals. The charred table is directly observable in a way that damage to one’s body from exposure to radioisotopes is not (partly because the table doesn’t have an immune system that kicks in to try to counter the damage). But the invisibility of these risks was also enhanced when manufacturers who used radioactive materials proclaimed their safety for both the end-user of consumer products and the workers making those products, and when the nuclear energy industry throttled the information the public got about mishaps at various nuclear reactors.

Possibly some of David Hahn’s teachers could have given him a more accurate view of the kinds of hazards he might undertake in trying to build a back yard breeder reactor … but the teen didn’t seem to feel like he could get solid mentoring from any of them, and didn’t let them in on his plans in any detail. The guidance he got from the Boy Scouts came in the form of an atomic energy merit badge pamphlet authored by the Atomic Energy Commission, a group created to promote atomic energy, and thus one unlikely to foreground the risks. (To be fair, this merit badge pamphlet did not anticipate that scouts working on the badge would actually take it upon themselves to build breeder reactors.) Presumably some of the scientists with whom David Hahn corresponded to request materials and advice on reactions would have emphasized the risks of his activities had they realized that they were corresponding with a high school student undertaking experiments in his back yard rather than with a science teacher trying to get clear on conceptual issues.

Each of these gaps of information ended up coalescing in such a way that David Hahn got remarkably close to his goal. He did an impressive job isolating radioactive materials from consumer products, performing chemical reactions to put them in suitable form for a breeder reactor, and assembling the pieces that might have initiated a chain reaction. He also succeeded in turning the back yard shed in which he conducted his work into a Superfund site. (According to Silverstein, the official EPA clean-up missed materials that his father and step-mother found hidden in their house and discarded in their household trash — which means that both the EPA and those close enough to the local landfill where the radioactive materials ended up had significant gaps in their knowledge about the hazards David Hahn introduced to the environment.)

The Radioactive Boy Scout manages to be at once an engaging walk through a challenging set of scientific problems and a chilling look at what can happen when scientific problems are stripped out of their real-life context of potential impacts for good and for ill that stretch across time and space and impact people who aren’t even aware of the scientific work being undertaken. It is a book I suspect my 13-year-old would enjoy very much.

I’m just not sure I’m ready to give it to her.

What does a Ph.D. in chemistry get you?

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A few weeks back, Chemjobber had an interesting post looking at the pros and cons of a PhD program in chemistry at a time when job prospects for PhD chemists are grim. The post was itself a response to a piece in the Chronicle of Higher Education by a neuroscience graduate student named Jon Bardin which advocated strongly that senior grad students look to non-traditional career pathways to have both their Ph.D.s and permanent jobs that might sustain them. Bardin also suggested that graduate students “learn to approach their education as a series of learning opportunities rather than a five-year-long job interview,” recognizing the relative luxury of having a “safe environment” in which to learn skills that are reasonably portable and useful in a wide range of career trajectories — all while taking home a salary (albeit a graduate-stipend sized one).

Chemjobber replied:

Here’s what I think Mr. Bardin’s essay elides: cost. His Ph.D. education (and mine) were paid for by the US taxpayer. Is this the best deal that the taxpayer can get? As I’ve said in the past, I think society gets a pretty good deal: they get 5+ years of cheap labor in science, (hopefully) contributions to greater knowledge and, at the end of the process, they get a trained scientist. Usually, that trained scientist can go on to generate new innovations in their independent career in industry or academia. It’s long been my supposition that the latter will pay (directly and indirectly) for the former. If that’s not the case, is this a bargain that society should continue to support? 

Mr. Bardin also shows a great deal of insouciance about the costs to himself: what else could he have done, if he hadn’t gone to graduate school? When we talk about the costs of getting a Ph.D., I believe that we don’t talk enough about the sheer length of time (5+ years) and what other training might have been taken during that time. Opportunity costs matter! An apprenticeship at a microbrewery (likely at a similar (if not higher) pay scale as a graduate student) or a 1 or 2 year teaching certification process easily fits in the half-decade that most of us seem to spend in graduate school. Are the communications skills and the problem-solving skills that he gained worth the time and the (opportunity) cost? Could he have obtained those skills somewhere else for a lower cost? 

Chemjobber also note that while a Ph.D. in chemistry may provide tools for range of careers, actually having a Ph.D. in chemistry on your resume is not necessarily advantageous in securing a job in one of those career.

As you might imagine this is an issue to which I have given some thought. After all, I have a Ph.D. in chemistry and am not currently employed in a job that is at all traditional for a Ph.D. in chemistry. However, given that it has been nearly two decades since I last dipped a toe into the job market for chemistry Ph.D.s, my observations should be taken with a large grain of sodium chloride.

First off, how should one think of a Ph.D. program in chemistry? There are many reasons you might value a Ph.D. program. A Ph.D. program may be something you value primarily because it prepares you for a career of a certain sort. It may also be something you value for what it teaches you, whether about your own fortitude in facing challenges, or about how the knowledge is built. Indeed, it is possible — maybe even common — to value your Ph.D. program for more than one of these reasons at a time. And some weeks, you may value it primarily because it seemed like the path of least resistance compared to landing a “real job” right out of college.

I certainly don’t think it’s the case that valuing one of these aspects of a Ph.D. program over the others is right or wrong. But …

Economic forces in the world beyond your graduate program might be such that there aren’t as many jobs suited to your Ph.D. chemist skills as there are Ph.D. chemists competing for those jobs. Among other things, this means that earning a Ph.D. in chemistry does not guarantee you a job in chemistry on the other end.

To which, as the proud holder of a Ph.D. in philosophy, I am tempted to respond: join the club! Indeed, I daresay that recent college graduates in many, many majors have found themselves in a world where a bachelors degree guarantees little except that the student loans will still need to be repaid.

To be fair, my sense is that the mismatch between supply of Ph.D. chemists and demand for Ph.D. chemists in the workplace is not new. I have a vivid memory of being an undergraduate chemistry major, circa 1988 or 1989, and being told that the world needed more Ph.D. chemists. I have an equally vivid memory of being a first-year chemistry graduate student, in early 1990, and picking up a copy of Chemical & Engineering News in which I read that something like 30% too many Ph.D. chemists were being produced given the number of available jobs for Ph.D. chemists. Had the memo not reached my undergraduate chemistry professors? Or had I not understood the business model inherent in the production of new chemists?

Here, I’m not interested in putting forward a conspiracy theory about how this situation came to be. My point is that even back in the last millennium, those in the know had no reason to believe that making it through a Ph.D. program in chemistry would guarantee your employment as a chemist.

So, what should we say about this situation?

One response to this situation might be to throttle production of Ph.D. chemists.

This might result in a landscape where there is a better chance of getting a Ph.D. chemist job with your Ph.D. in chemistry. But, the market could shift suddenly (up or down). Were this to happen, it would take time to adjust the Ph.D. throughput in response. As well, current PIs would have to adjust to having fewer graduate students to crank out their data. Instead, they might have to pay more technicians and postdocs. Indeed, the number of available postdocs would likely drop once the number of Ph.D.s being produced more closely matched the number of permanent jobs for holders of those Ph.D.s.

Needless to say, this might be a move that the current generation of chemists with permanent positions at the research institutions that train new chemists would find unduly burdensome.

We might also worry about whether the thinning of the herd of chemists ought to happen on the basis of bachelors-level training. Being a successful chemistry major tends to reflect your ability to learn scientific knowledge, but it’s not clear to me that this is a great predictor of how good you would be at the project of making new scientific knowledge.

In fact, the thinning of the herd wherever it happens seems to put a weird spin on the process of graduate-level education. Education, after all, tends to aim for something bigger, deeper, and broader than a particular set of job skills. This is not to say that developing skills is not an important part of an education — it is! But in addition to these skills, one might want an understanding of the field in which one is being educated and its workings. I think this is connected to how being a chemist becomes linked to our identity, a matter of who we are rather than just of what we do.

Looked at this way, we might actually wonder about who could be harmed by throttling Ph.D. program enrollments.

Shouldn’t someone who’s up for the challenge have that experience open to her, even if there’s no guarantee of a job at the other end? As long as people have accurate information with which to form reasonable expectations about their employment prospects, do we want to be paternalistic and tell them they can’t?

(There are limits here, of course. There are not unlimited resources for the training of Ph.D. chemists, nor unlimited slots in graduate programs, nor in the academic labs where graduate students might participate meaningfully in research. The point is that maybe these limits are the ones that ought to determine how many people who want to learn how to be chemists get to do that.)

Believe it or not, we had a similar conversation in a graduate seminar filled with first and second year students in my philosophy Ph.D. program. Even philosophy graduate students have an interest in someday finding stable employment, the better to eat regularly and live indoors. Yet my sense was that even the best graduate students in my philosophy Ph.D. program recognized that employment in a job tailor-made for a philosophy Ph.D. was a chancy thing. Certainly, there were opportunity costs to being there. Certainly, there was a chance that one might end up trying to get hired to a job for which having a PhD would be viewed as a disadvantage to getting hired. But the graduate students in my philosophy program had, upon weighing the risks, decided to take the gamble.

How exactly are chemistry graduate students presumed to be different here? Maybe they are placing their bets at a table with higher payoffs, and where the game is more likely to pay off in the first place. But this is still not a situation in which one should expect that everyone is always going to win. Sometimes the house will win instead.

(Who’s the house in this metaphor? Is it the PIs who depend on cheap grad-student labor? Universities with hordes of pre-meds who need chemistry TAs and lab instructors? The public that gets a screaming deal on knowledge production when you break it down in terms of price per publishable unit? A public that includes somewhat more members with a clearer idea of how scientific knowledge is built? Specifying the identity of the house is left as an exercise for the reader.)

Maybe the relevant difference between taking a gamble on a philosophy Ph.D. and taking a gamble on a chemistry Ph.D. is that the players in the latter have, purposely or accidentally, not been given accurate information about the odds of the game.

I think it’s fair for chemistry graduate students to be angry and cynical about having been misled as far as likely prospects for employment. But given that it’s been going on for at least a couple decades (and maybe more), how the hell is it that people in Ph.D. programs haven’t already figured out the score? Is it that they expect that they will be the ones awesome enough to get those scarce jobs? Have they really not thought far enough ahead to seek information (maybe even from a disinterested source) about how plausible their life plans are before they turn up at grad school? Could it be that they have decided that they want to be chemists when they grow up without doing sensible things like reading the blogs of chemists at various stages of careers and training?

Presumably, prospective chemistry grad students might want to get ahold of the relevant facts and take account of them in their decision-making. Why this isn’t happening is somewhat mysterious to me, but for those who regard their Ph.D. training in chemistry as a means to a career end, it’s absolutely crucial — and trusting the people who stand to benefit from your labors as a graduate student to hook you up with those facts seems not to be the best strategy ever.

And, as I noted in comments on Chemjobber’s post, the whole discussion suggests to me that the very best reason to pursue a Ph.D. in chemistry is because you want to learn what it is like to build new knowledge in chemistry, in an academic setting. Since being plugged into a particular kind of career (or even job) on the other end is a crap-shoot, if you don’t want to learn about this knowledge-building process — and want it enough to put up with long hours, crummy pay, unrewarding piles of grading, and the like — then possibly a Ph.D. program is not the best way to spend 5+ years of your life.

Crime, punishment, and the way forward: in the wake of Sheri Sangji’s death, what should happen to Patrick Harran?

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When bad things happen in an academic laboratory, what should happen to people who bear responsibility for those bad things — even if they didn’t mean for them to happen?

This is the broad question I’ve been thinking about in connection with the prosecution of chemistry professor Patrick Harran and UCLA in connection with the laboratory accident that killed Sheri Sangji. Potentially, Harran could face jail time, and there has been a good bit of discussion (as in these posts at Chemjobber) about whether that’s what he deserves.

I’ll be honest: I find myself uncomfortable weighing Harran’s actions (and inaction) as worthy of jail time or not, let alone assigning the appropriate number of months or years behind bars to punish him for Sheri Sangji’s death. And, other than satisfying our appetite for retribution, I am utterly unsure whether such a penalty in this case would help. I don’t know that it would do much to change the conditions and institutions that ought to be changed in the wake of this accident. (On the matter of changing institutions, read the excellent posts at ChemBark and Chemjobber.)

Sheri Sangji’s death should alert us that things need to change. Conditions in academic labs need to change. Attitudes and behaviors of PIs, students, and technicians need to change. University departments (which are both builders of knowledge and trainers of new scientists) need to change. What kind of resolution of the prosecution of Prof. Harran could bring about the needed changes?

The best way forward should keep lab accidents like the one that killed Sheri Sangji from happening again. Of course, if we’re talking about avoiding such lab accidents, we’re assuming this one was preventable through some combination of proper safety equipment and attire, training, supervision, and the like.

Jailing the PI would certainly get the attention of other PIs and would underline the message that they are responsible for safety in their labs, as well as for addressing deficiencies identified in safety inspections (and maybe even for identifying and addressing the deficiencies themselves). Maybe jailing the PI in this case would also make Sheri Sangji’s family feel that justice had been served.

But, jailing the PI here might also move him, and the larger problem of making research activities reliably non-lethal, out of the sight of the people who really need to be focused on learning the lesson here.

Maybe jail would make him appear like more of the monster; his lab must have been much worse than ours. Or maybe his absence from the academic research milieu might simply mean the other PIs would return their focus to the pressing problems of securing funding, generating data, and cranking out manuscripts. Perhaps their institutions would be stricter about future safety inspections, but the PIs would do what they needed to do to return to the business as usual. Given the extent to which universities rely on external grants secured by such scientific business-as-usual, it’s hard to imagine universities doing much to shake PIs out of this routine.

If we’re interested in justice that actually addresses the dangers of business as usual, I think there is another option we should explore.

I don’t think Prof. Harran should be allowed to continue with the lines of research he was pursuing when the accident in his lab claimed Sheri Sangji’s life. The way he conducted that research — the way he supervised activities and personnel — killed someone employed to advance the research. That’s a big enough strike to bench him and let other PIs play that knowledge-building zone.

Instead, Harran should devote the remainder of his career to creating a scientific culture — at UCLA and beyond — in which the safety of the people performing the experiments (and making the reagents, and fixing the equipment, and cleaning the glassware) is never sacrificed to the goal of getting more and faster results. His mission should be to communicate just how easy it was for a “good PI” to allow lapses in safe procedures, to assume students and staff will figure out how to be safe when using materials or techniques that are new to them, to find tasks more important than supervising lab work, to discourage questions about how to be safe.

This shouldn’t be a new service requirement on Harran in addition to his research and his teaching. This should be the core of his job.

He should not only grapple with the soul-searching a decent person does when he’s allowed conditions that have killed and underling, but also do that soul-searching in a space where the rest of the scientific community can participate and include themselves in the examination. Harran’s presence in this role — his active involvement with his department in this role — means that Sheri Sangji and the circumstances that killed her will not be forgotten.

Since research grants would be unlikely to pay for this new set of professorial professional responsibilities — and since UCLA likely bears some share of responsibility for creating the conditions that killed Sheri Sangji — UCLA should fully fund these new responsibilities of Harran’s position moving forward. As well, UCLA should provide what support is necessary to allow Harran’s colleagues (and students and other personnel in their labs) to adapt their own practices in ways that incorporate his lessons. And, it might have a meaningful impact if professional organizations like the American Chemical Society provided funds for Harran to travel and speak to others running academic labs about how to make them safer.

In short, my hunch is that the best way to achieve progress on safe conditions and practices (not to mention relationships in lab groups that help everyone promote safety) is not to separate Harran from his professional community but to return him to that community with a new mission. His new charge would be to help build a better business-as-usual.

It might not be the science career he envisioned, but I reckon it’s a job that needs doing. Harran now has ample first-hand knowledge of why it matters.

Suit against UCLA in fatal lab fire raises question of who is responsible for safety.

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Right before 2011 ended (and, as it happened, right before the statute of limitations ran out), the Los Angeles County district attorney’s office filed felony charges against the University of California regents and UCLA chemistry professor Patrick Harran in connection with a December 2008 fire in Harran’s lab that resulted in the death of a 23-year-old staff research assistant, Sheharbano “Sheri” Sangji.

As reported by The Los Angeles Times:

Harran and the UC regents are charged with three counts each of willfully violating occupational health and safety standards. They are accused of failing to correct unsafe work conditions in a timely manner, to require clothing appropriate for the work being done and to provide proper chemical safety training.

Harran, 42, faces up to 4½ years in state prison, Robison said. He is out of town and will surrender to authorities when he returns, said his lawyer, Thomas O’Brien, who declined to comment further.

UCLA could be fined up to $1.5 million for each of the three counts.

[UCLA vice chancellor for legal affairs Kevin] Reed described the incident as “an unfathomable tragedy,” but not a crime.

The article notes that Sangji was working as a staff research assistant in Harran’s lab while she was applying to law schools. It mentions that she was a 2008 graduate of Pomona College but doesn’t mention whether she had any particular background in chemistry.

As it happens, the work she was doing in the Harran lab presented particular hazards:

Sangji was transferring up to two ounces of t-butyl lithium from one sealed container to another when a plastic syringe came apart in her hands, spewing a chemical compound that ignites when exposed to air. The synthetic sweater she wore caught fire and melted onto her skin, causing second- and third-degree burns.

In May 2009, Cal/OSHA fined UCLA a total of $31,875 after finding that Sangji had not been trained properly and was not wearing protective clothing.

Two months before the fatal fire, UCLA safety inspectors found more than a dozen deficiencies in the same lab, according to internal investigative and inspection reports reviewed by The Times. Inspectors found that employees were not wearing requisite protective lab coats and that flammable liquids and volatile chemicals were stored improperly.

Corrective actions were not taken before the fire, the records showed.

Actions to address the safety deficiencies were taken after the fire, but these were, obviously, too late to save Sangji.

I’m not a lawyer, and I’m not interested in talking about legalities here — whether for the particular case the Los Angeles DA’s office will be pursuing against UCLA or for academic research labs more generally.

Rather, I want to talk about ethics.

Knowledge-building can be a risky business. In some situations, it involves materials that pose direct dangers to the people handling them, to the people in the vicinity, and even to people some distance away who are just trying to get on with their lives (e.g., if the hazardous materials get out into our shared environment).

Generally, scientists doing research that involves hazardous materials do what they can to find out how to mitigate the hazards. They learn appropriate ways of handling the materials, of disposing of them, of protecting themselves and others in case of accidents.

But, knowing the right ways to deal with hazardous materials is not sufficient to mitigate the risks. Proper procedures need to be implemented. Otherwise, your knowledge about the risks of hazardous materials is mostly useful in explaining bad outcomes after they happen.

So, who is ethically responsible for keeping an academic chemistry lab safe? And what exactly is the shape this responsibility takes — that is, what should he or she be doing to fulfill that obligation?

What’s the responsibility of the principal investigator, the scientist leading the research project and, in most cases, heading the lab?

What’s the responsibility of the staff research assistant or technician, doing necessary labor in the lab for a paycheck?

What’s the responsibility of the graduate student in the research group, trying to learn how to do original research and to master the various skills he or she will need to become a PI someday? (It’s worth noting here that there’s a pretty big power differential between grad students and PIs, which may matter as far as how we apportion responsibility. Still, this doesn’t mean that those with less power have no ethical obligations pulling on them.)

What’s the responsibility of the institution under whose auspices the lab is operating? When a safety inspection turns up problems and issues a list of issues that must be corrected, has that responsibility been discharged? When faculty members hire new staff research assistants, or technicians, or graduate students, does the institution have any specific obligations to them (as far as providing safety training, or a place to bring their safety concerns, or protective gear), or does this all fall to the PI?

And, what kind of obligations do these parties have in the case that one of the other players falls down on some of his or her obligations?

If I were still working in a chemistry lab, thinking through ethical dimensions like these before anything bad happened would not strike me as a purely academic exercise. Rather, it would be essential to ensuring that everyone stays as safe as possible.

So, let’s talk about what that would look like.

Science kits … for girls.

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Via a tweet from Ed Yong, I discovered this weekend (not that I couldn’t have guessed) that purveyors of science kits for kids are still gendering the heck out of them. That is to say, there are science kits, and there are science kits for girls.

For all I know, putting science kits in pink boxes is an excellent strategy to get them to fly off the shelves, but I am not convinced that it is a good strategy when it comes to getting girls interested in science. Indeed, I worry that whatever interest in science kits like these might cultivate might come with baggage that could actually make it harder for girls (and the women they become) to pursue scientific education and careers.

I’ll try to spell out the shape of these worries in my next post. In this post, I offer for your consideration, three “science” kits targeted at girls that appeared in toy catalogues that crossed my desk five years ago. Then, I’ll take a quick look at this year’s offerings.

Archimedes got scientific insight from a bathtub, but he wasn't required to wear eye-makeup to do it.

Spa Science

The kit offers itself as a way “to cultivate a girl’s interest in science” through the making of “beauty products like an oatmeal mask, rose bath balm, and aromatherapy oils”. Besides the “natural and organic materials” to concoct said products, the kit includes “a booklet that explores how scents affect moods and memories.”

Don’t get me wrong — there is science worth discussing in this neighborhood.

But, the packaging here strikes me as selling the need for beauty product more emphatically than any underlying scientific explanations of how they work. Does a ten-year-old need an oatmeal mask? (If so, why only ten-year-old girls? Do not ten-year-old boys have pores and sebaceous glands?) Also, I’m nervous that the exploration of scents and “aromatherapy” may be setting kids up as easy marks for health food grocers and metaphysical bookstores who will sell them all manner of high-priced, over-hyped, essential-oil-containing stuff.

Maybe the Barbie-licious artwork is intended to convey that even very “girly” girls can find some element of science that is important to their concerns, but it seems also to convey that being overtly feminine is a concern that all girls have (or ought to have) — and, that such “girly” girls couldn’t possibly take an interest in science except as a way to cultivate their femininity.

Our exposed shoulders tell you that you can do these activities without being a tomboy!

Perfumery

Aimed at a slightly younger audience (of “young ladies-in-training”) than the last kit, this one promises to teach girls “the chemistry behind” perfumes. Setting aside my skepticism about how much real engagement with chemistry one is likely to get from a kit like this, notice that the catalogue blurb starts with the claim that “Everyone should have a ‘signature scent’!” (I beg to differ. My ten-year-old’s signature scent is soap, thank you very much.) Does the benefit of teaching a kid a little bit of chemistry outweigh the cost of convincing a little girl that she ought to smell like something other than a young human? Where might this lead?

And where are the boys here? Aren’t they supposed to be grooming boys to want to buy fragrances, too? Here’s a conjecture for the field operatives to explore further: Males are sold fragrances as a way to render females helpless to the males’ sexual magnetism, whereas females are sold fragrances as a way to smell acceptable. Plus, boys just naturally dig science, whereas girls just naturally dig laboring under the weight of gender roles.

Would these products make me feel as pretty without those little tubes and pots?

Creative Cosmetics

Here’s another — substantially pricier kit — aiming to teach a little science through the mixing and application of “customized skin care items”, although again the assumption seems to be that only girls have skin that requires care, or that only girls need to be suckered into caring about science. Cynic that I am, I cannot help but wonder how much of the “important skin care and wellness facts” included with the essential oils, packaging, and instructions is devoted to actual science as opposed to cultivating an unnecessary beauty regimen.

Given that this kit “teaches them to make shampoos and shower gels, makeup, creams and lotions from common household items” — which, presumably, one’s household may already have — what could explain the high price of this kit ($60)? My bet is on the little pots and tubes and squeeze bottles — which is to say, on the part that has nothing at all to do with the quality of the skin care product, and everything to do with making you want to buy it when you see it in the store.
But surely, this kit really is intended to cultivate an interest in science rather than train new generations of consumers, right?

Casting an eye to the recent crop of girls’ science kits, I get the feeling that consumerism is the intended goal.

We see thirteen distinct kits (collect them all!), four of which are centered on growing crystals. (To be fair, one of these is advertised as combining the experiments of two of the other three.) Three of the kits are focused on perfumes, although each involves different activities (making incense, or cards and “dazzling cloth hangings,” or scented gel crystals and perfumed slime). There is a “Luxury Soap Lab” kit as well as a “Beauty Spa Lab” kit with which you can make … fancy soaps. I’m guessing that these kits are separate not to keep the retail prices down, but to encourage kids (or the people purchasing gifts for them) to buy more of them.

Plus, the description of the “Beauty Spa Lab” notes that you can make “scrub soaps for dad, or exfoliating soaps for mum.” Which is to say, the gendering is pretty thoroughgoing here.

Perhaps it’s a tiny step in the right direction that one of the girls’ kits is “Beautiful Blob Slime”. Non-Newtonian semi-solids are cool and don’t in themselves cram gendered expectations down a girl’s throat. Still, the assumption is that a girl must be reassured of the beauty of the slime before she’ll play.

Honestly, I can’t think of a better way to make a girl in grade school question whether she’ll have any interest in or aptitude for science than to present her with a “science for girls” kit. The message seems to be, “Look, there’s a bit of science that will interest even you. (And go put on some lipstick!)” Heaven knows, we couldn’t even get girls interested in building Rube Goldberg machines, or launching water-rockets, or studying the growth of plants or the behaviors of animals, or blowing stuff up … except, these are just the sort of things that the girls I know would want to do, even the pretty pink princesses.

Moreover, it seems to me a kid could explore some of this same scientific territory without coughing up $60, or even $25.

As a place to start, check out the American Chemical Society’s kids’ website.

The hands-on activities include nine fun experiments with soap and detergent, three with crystals, six with polymers, and eleven with food, just for starters. These activities can be done with materials you probably already have in the house (or can find easily in a grocery store). And, as an added bonus, none of them are labeled as experiments for girls or experiments for boys. They are experiments for whatever kid (or grown-up) want to do them.

Up next, I’ll explain why I think bundling kids’ science kids with gendered stereotypes is a bad idea both in the short term and in the long run.

Why does Thanksgiving dinner make you sleepy?

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Thanksgiving DessertsFor years, you’ve heard the tremendous fatigue experienced after an American Thanksgiving dinner laid at the feet of the turkey — or more precisely, blamed upon the tryptophan in that turkey. Trytophan, apparently, is the go-to amino acid for those who want to get sleepy.

Let me note, before we go on, that for all its association with tryptophan, turkey doesn’t even crack the top 50 in this list of tryptophan-rich foods. (Number one: stellar sea lion kidney.)

In any case, according to an article in the Los Angeles Times, that appeared in time for Thanksgiving 2008, the real story may be more complicated than that:

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