Facing felony charges in lab death of Sheri Sangji, UCLA settles, Harran stretches credulity.

There have been recent developments in the criminal case against UCLA and chemistry professor Patrick Harran in connection with the fatal laboratory accident that resulted in the death of Sheri Sangji (which we’ve discussed here and here). The positive development is that UCLA has reached a plea agreement with prosecutors. (CORRECTION: UCLA has reached a settlement agreement with the prosecutors, not a plea agreement. Sorry for the confusion.) However, Patrick Harran’s legal strategy has taken a turn that strikes me as ill-advised.

From the Los Angeles Times:

Half of the felony charges stemming from a 2008 lab accident that killed UCLA research assistant Sheri Sangji were dropped Friday when the University of California regents agreed to follow comprehensive safety measures and endow a $500,000 scholarship in her name.

“The regents acknowledge and accept responsibility for the conditions under which the laboratory operated on Dec. 29, 2008,” the agreement read in part, referring to the date that Sangji, 23, suffered fatal burns.

Charges remain against her supervisor, chemistry professor Patrick Harran. His arraignment was postponed to Sept. 5 to allow the judge to consider defense motions, including one challenging the credibility of the state’s chief investigator on the case. …

UCLA and Harran have called her death a tragic accident and said she was a seasoned chemist who chose not to wear a protective lab coat. …

In court papers this week, Harran’s lawyers said prosecutors had matched the fingerprints of Brian Baudendistel, a senior special investigator who handled the case for the state Division of Occupational Safety and Health, with the prints of a teenager who pleaded no contest to murder in Northern California in 1985.

The defense contends that the investigator, whose report formed the basis for the charges, is the same Brian A. Baudendistel who took part in a plot to rob a drug dealer of $3,000 worth of methamphetamine, then shot him. Another teenager admitted to pulling the trigger but said it was Baudendistel’s shotgun.

Baudendistel told The Times this week that it is a case of mistaken identity and that he is not the individual involved in the 1985 case.

Cal/OSHA defended the integrity of the investigation in a statement issued Friday by spokesman Dean Fryer.

“The defendants’ most recent attempt to deflect attention from the charges brought against them simply does not relate in any way to the circumstances of Ms. Sangji’s death or the actual evidence collected in Cal/OSHA’s comprehensive investigation,” it read.

Deborah Blum adds:

Should  chemist-in-training approach hazardous chemicals with extreme caution? Yes. Should she expect her employer to provide her with the necessary information and equipment to engage in such caution? Most of us would argue yes. Should chemistry professors be held to the standard of employee safety as, say, chemical manufacturers or other industries? The most important “yes” to that question comes from  Cal/OSHA senior  investigator Brian Baudendistal.

Baudendistal concluded that the laboratory operation was careless enough for long enough to justify felony charges of willful negligence.  The Sangji family, angered by those suggestions that Sheri’s experience should have taught her better, pushed for prosecution. Late last year the Los Angeles District Attorney’s office  officially brought charges against Harran, UCLA, and the University of California system itself. …

[Harran’s] lawyers have responded to the Baudendistal report in part by focusing on Baudendistal himself. They claim to have found evidence that in 1985 he and two friends conspired to set up the murder of a drug dealer. All three boys were convicted and although, since they were juveniles, the records were sealed, attorneys were able to identify the killers through press coverage at the time. Although Baudendistal has insisted that Harran’s defense team tracked down the wrong man, they say they have a fingerprint match to prove it. They say further that a man who covers up his past history is not credible – and therefore neither is is report on the UCLA laboratory.

I am not a lawyer, so I’m not terribly interested in speculating on the arcane legal considerations that might be driving this move by Harran’s legal team. (Chemjobber speculates that it might be a long shot they’re playing amid plea negotiations that are not going well.)

As someone with a professional interest in crime and punishment within scientific communities, and in ethics more broadly, I do, however, think it’s worth examining the logic of Patrick Harran’s legal strategy.

The strategy, as I understand it, is to cast aspersions on the Cal/OSHA report on the basis of the legal history of the senior investigator that prepared it — specifically, his alleged involvement as a teenager in 1985 in a murder plot.

Does a past bad act like this serve as prima facie reason to doubt the accuracy of the report of the investigation of conditions in Harran’s lab? It’s not clear how it could, especially if there were other investigators on the team, not alleged to be involved in such criminal behavior, who endorsed the claims in the report.

Unless, of course, the reason Harran’s legal team thinks we should doubt the accuracy of the report is that the senior investigator who prepared it is a habitual liar. To support the claim that he cannot be trusted, they point to a single alleged lie — denying involvement in the 1985 murder plot.

But this strikes me as a particularly dangerous strategy for Patrick Harran to pursue.

Essentially, the strategy rests on the claim that if a person has lied about some particular issue, we should assume that any claim that person makes, about whatever issue, might also be a lie. I’m not unsympathetic to this claim — trust is something that is earned, not simply assumed in the absence of clear evidence of dishonesty.

However, this same reasoning cannot help Patrick Harran’s credibility, given that he is on record describing Sheri Sangji, a 23-year-old with a bachelor’s degree, as an experienced chemist. Many have noted already that claiming Sheri Sangji was a experienced chemist is ridiculous on its face.

Thus, it’s not unreasonable to conclude that Patrick Harran lied when he described Sheri Sangji as an experienced chemist. And, if this is the case, following the reasoning advocated by his legal team, we must doubt the credibility of every other claim he has made — including claims about the safety training he did or did not provide to people in his lab, conditions in his lab in 2008 when the fatal accident happened, even whether he recommended that Sangji wear a lab coat.

If Patrick Harran was not lying when he said he believed Sheri Sangji was an experienced chemist, the other possibility is that he is incredibly stupid — certainly too stupid to be in charge of a lab where people work with potentially hazardous chemicals.

Some might posit that Harran’s claims about Sangji’s chemical experience were made on the advice of his legal team. That may well be, but I’m unclear on how lying on the advice of counsel is any less a lie. (If it is, this might well mitigate the “lie of omission” of an investigator advised by his lawyers that his juvenile record is sealed.) And if one lie is all it takes to decimate credibility, Harran is surely as vulnerable as Baudendistel.

Finally, a piece of free advice to PIs worrying that they may find themselves facing criminal charges should their students, postdocs, or technicians choose not to wear lab coats or other safety gear: It is perfectly reasonable to establish, and enforce, a lab policy that states that those choosing to opt out of the required safety equipment are also opting out of access to the laboratory.

The purpose of a funding agency (and how that should affect its response to misconduct).

In the “Ethics in Science” course I regularly teach, students spend a good bit of time honing their ethical decision-making skills by writing responses to case studies. (A recent post lays out the basic strategy we take in approaching these cases.) Over the span of the semester, my students’ responses to the cases give me pretty good data about the development of their ethical decision-making.

From time to time, they also advance claims that make me say, “Hmmm …”

Here’s one such claim, recently asserted in response to a case in which the protagonist, a scientist serving on a study section for the NIH (i.e., a committee that ranks the merit of grant proposals submitted to the NIH for funding), has to make a decision about how to respond when she detects plagiarism in a proposal:

The main purpose of the NIH is to ensure that projects with merit get funded, not to punish scientists for plagiarism.

Based on this assertion, the student argued that it wasn’t clear that the study section member had to make an official report to the NIH about the plagiarism.

I think the claim is interesting, though I think maybe we would do well to unpack it a little. What, for instance, counts as a project with merit?

Is it enough that the proposed research would, if successful, contribute a new piece of knowledge to our shared body of scientific knowledge? Does the anticipated knowledge that the research would generate need to be important, and if so, according to what metric? (Clearly applicable to a pressing problem? Advancing our basic understanding of some part of our world? Surprising? Resolving an ongoing scientific debate?) Does the proposal need to convey evidence that the proposers have a good chance at being successful in conducting the research (because they have the scientific skills, the institutional resources, etc.)?

Does plagiarism count as evidence against merit here?

Perhaps we answer this question differently if we think what should be evaluated is the proposal rather than the proposer. Maybe the proposed research is well-designed, likely to work, and likely to make an important contribution to knowledge in the field — even if the proposer is judged lacking in scholarly integrity (because she seems not to know how properly to cite the words or ideas of others, or not to care to do so if she knows how).

But, one of the expectations of federal funders like the NIH is that scientists whose research is funded will write up the results and share them in the scientific literature. Among other things, this means that one of the scientific skills that a proposer will need to see a project through to completion (including publishing the results) successfully is the ability to write without running afoul of basic standards of honest scholarship. A paper which communicates important results while also committing plagiarism will not bring glory to the NIH for funding the researcher.

More broadly, the fact that something (like detecting or punishing plagiarism) is not a primary goal does not mean it is not a goal that might support the primary goal. To the extent that certain kinds of behavior in proposing research might mark a scientist as a bad risk to carry out research responsibly, it strikes me as entirely appropriate for funding agencies to flag those behaviors when they see them — and also to share that information with other funding agencies.

As well, to the extent that an agency like the NIH might punish a scientist for plagiarism, the kind of punishment it imposes is generally barring that scientist from eligibility for funding for a finite number of years. In other words, the punishment amounts to “You don’t get our money, and you don’t get to ask us for money again for the next N years.” To me, this punishment doesn’t look like it’s disproportional, and it doesn’t look like imposing it on a plagiarist grant proposer diverges wildly from the main goal of ensuring that projects with merit get funded.

But, as always, I’m interested in what you all think about it.

Crime, punishment, and the way forward: in the wake of Sheri Sangji’s death, what should happen to Patrick Harran?

When bad things happen in an academic laboratory, what should happen to people who bear responsibility for those bad things — even if they didn’t mean for them to happen?

This is the broad question I’ve been thinking about in connection with the prosecution of chemistry professor Patrick Harran and UCLA in connection with the laboratory accident that killed Sheri Sangji. Potentially, Harran could face jail time, and there has been a good bit of discussion (as in these posts at Chemjobber) about whether that’s what he deserves.

I’ll be honest: I find myself uncomfortable weighing Harran’s actions (and inaction) as worthy of jail time or not, let alone assigning the appropriate number of months or years behind bars to punish him for Sheri Sangji’s death. And, other than satisfying our appetite for retribution, I am utterly unsure whether such a penalty in this case would help. I don’t know that it would do much to change the conditions and institutions that ought to be changed in the wake of this accident. (On the matter of changing institutions, read the excellent posts at ChemBark and Chemjobber.)

Sheri Sangji’s death should alert us that things need to change. Conditions in academic labs need to change. Attitudes and behaviors of PIs, students, and technicians need to change. University departments (which are both builders of knowledge and trainers of new scientists) need to change. What kind of resolution of the prosecution of Prof. Harran could bring about the needed changes?

The best way forward should keep lab accidents like the one that killed Sheri Sangji from happening again. Of course, if we’re talking about avoiding such lab accidents, we’re assuming this one was preventable through some combination of proper safety equipment and attire, training, supervision, and the like.

Jailing the PI would certainly get the attention of other PIs and would underline the message that they are responsible for safety in their labs, as well as for addressing deficiencies identified in safety inspections (and maybe even for identifying and addressing the deficiencies themselves). Maybe jailing the PI in this case would also make Sheri Sangji’s family feel that justice had been served.

But, jailing the PI here might also move him, and the larger problem of making research activities reliably non-lethal, out of the sight of the people who really need to be focused on learning the lesson here.

Maybe jail would make him appear like more of the monster; his lab must have been much worse than ours. Or maybe his absence from the academic research milieu might simply mean the other PIs would return their focus to the pressing problems of securing funding, generating data, and cranking out manuscripts. Perhaps their institutions would be stricter about future safety inspections, but the PIs would do what they needed to do to return to the business as usual. Given the extent to which universities rely on external grants secured by such scientific business-as-usual, it’s hard to imagine universities doing much to shake PIs out of this routine.

If we’re interested in justice that actually addresses the dangers of business as usual, I think there is another option we should explore.

I don’t think Prof. Harran should be allowed to continue with the lines of research he was pursuing when the accident in his lab claimed Sheri Sangji’s life. The way he conducted that research — the way he supervised activities and personnel — killed someone employed to advance the research. That’s a big enough strike to bench him and let other PIs play that knowledge-building zone.

Instead, Harran should devote the remainder of his career to creating a scientific culture — at UCLA and beyond — in which the safety of the people performing the experiments (and making the reagents, and fixing the equipment, and cleaning the glassware) is never sacrificed to the goal of getting more and faster results. His mission should be to communicate just how easy it was for a “good PI” to allow lapses in safe procedures, to assume students and staff will figure out how to be safe when using materials or techniques that are new to them, to find tasks more important than supervising lab work, to discourage questions about how to be safe.

This shouldn’t be a new service requirement on Harran in addition to his research and his teaching. This should be the core of his job.

He should not only grapple with the soul-searching a decent person does when he’s allowed conditions that have killed and underling, but also do that soul-searching in a space where the rest of the scientific community can participate and include themselves in the examination. Harran’s presence in this role — his active involvement with his department in this role — means that Sheri Sangji and the circumstances that killed her will not be forgotten.

Since research grants would be unlikely to pay for this new set of professorial professional responsibilities — and since UCLA likely bears some share of responsibility for creating the conditions that killed Sheri Sangji — UCLA should fully fund these new responsibilities of Harran’s position moving forward. As well, UCLA should provide what support is necessary to allow Harran’s colleagues (and students and other personnel in their labs) to adapt their own practices in ways that incorporate his lessons. And, it might have a meaningful impact if professional organizations like the American Chemical Society provided funds for Harran to travel and speak to others running academic labs about how to make them safer.

In short, my hunch is that the best way to achieve progress on safe conditions and practices (not to mention relationships in lab groups that help everyone promote safety) is not to separate Harran from his professional community but to return him to that community with a new mission. His new charge would be to help build a better business-as-usual.

It might not be the science career he envisioned, but I reckon it’s a job that needs doing. Harran now has ample first-hand knowledge of why it matters.

Suit against UCLA in fatal lab fire raises question of who is responsible for safety.

Right before 2011 ended (and, as it happened, right before the statute of limitations ran out), the Los Angeles County district attorney’s office filed felony charges against the University of California regents and UCLA chemistry professor Patrick Harran in connection with a December 2008 fire in Harran’s lab that resulted in the death of a 23-year-old staff research assistant, Sheharbano “Sheri” Sangji.

As reported by The Los Angeles Times:

Harran and the UC regents are charged with three counts each of willfully violating occupational health and safety standards. They are accused of failing to correct unsafe work conditions in a timely manner, to require clothing appropriate for the work being done and to provide proper chemical safety training.

Harran, 42, faces up to 4½ years in state prison, Robison said. He is out of town and will surrender to authorities when he returns, said his lawyer, Thomas O’Brien, who declined to comment further.

UCLA could be fined up to $1.5 million for each of the three counts.

[UCLA vice chancellor for legal affairs Kevin] Reed described the incident as “an unfathomable tragedy,” but not a crime.

The article notes that Sangji was working as a staff research assistant in Harran’s lab while she was applying to law schools. It mentions that she was a 2008 graduate of Pomona College but doesn’t mention whether she had any particular background in chemistry.

As it happens, the work she was doing in the Harran lab presented particular hazards:

Sangji was transferring up to two ounces of t-butyl lithium from one sealed container to another when a plastic syringe came apart in her hands, spewing a chemical compound that ignites when exposed to air. The synthetic sweater she wore caught fire and melted onto her skin, causing second- and third-degree burns.

In May 2009, Cal/OSHA fined UCLA a total of $31,875 after finding that Sangji had not been trained properly and was not wearing protective clothing.

Two months before the fatal fire, UCLA safety inspectors found more than a dozen deficiencies in the same lab, according to internal investigative and inspection reports reviewed by The Times. Inspectors found that employees were not wearing requisite protective lab coats and that flammable liquids and volatile chemicals were stored improperly.

Corrective actions were not taken before the fire, the records showed.

Actions to address the safety deficiencies were taken after the fire, but these were, obviously, too late to save Sangji.

I’m not a lawyer, and I’m not interested in talking about legalities here — whether for the particular case the Los Angeles DA’s office will be pursuing against UCLA or for academic research labs more generally.

Rather, I want to talk about ethics.

Knowledge-building can be a risky business. In some situations, it involves materials that pose direct dangers to the people handling them, to the people in the vicinity, and even to people some distance away who are just trying to get on with their lives (e.g., if the hazardous materials get out into our shared environment).

Generally, scientists doing research that involves hazardous materials do what they can to find out how to mitigate the hazards. They learn appropriate ways of handling the materials, of disposing of them, of protecting themselves and others in case of accidents.

But, knowing the right ways to deal with hazardous materials is not sufficient to mitigate the risks. Proper procedures need to be implemented. Otherwise, your knowledge about the risks of hazardous materials is mostly useful in explaining bad outcomes after they happen.

So, who is ethically responsible for keeping an academic chemistry lab safe? And what exactly is the shape this responsibility takes — that is, what should he or she be doing to fulfill that obligation?

What’s the responsibility of the principal investigator, the scientist leading the research project and, in most cases, heading the lab?

What’s the responsibility of the staff research assistant or technician, doing necessary labor in the lab for a paycheck?

What’s the responsibility of the graduate student in the research group, trying to learn how to do original research and to master the various skills he or she will need to become a PI someday? (It’s worth noting here that there’s a pretty big power differential between grad students and PIs, which may matter as far as how we apportion responsibility. Still, this doesn’t mean that those with less power have no ethical obligations pulling on them.)

What’s the responsibility of the institution under whose auspices the lab is operating? When a safety inspection turns up problems and issues a list of issues that must be corrected, has that responsibility been discharged? When faculty members hire new staff research assistants, or technicians, or graduate students, does the institution have any specific obligations to them (as far as providing safety training, or a place to bring their safety concerns, or protective gear), or does this all fall to the PI?

And, what kind of obligations do these parties have in the case that one of the other players falls down on some of his or her obligations?

If I were still working in a chemistry lab, thinking through ethical dimensions like these before anything bad happened would not strike me as a purely academic exercise. Rather, it would be essential to ensuring that everyone stays as safe as possible.

So, let’s talk about what that would look like.